Lantus SoloStar (insulin glargine injection) U-100 Pen

What is Lantus SoloStar (insulin glargine injection) U-100 Pen?

Lantus SoloStar (insulin glargine injection) U-100 Pen is a long-acting injectable insulin used to manage diabetes mellitus in pets, particularly cats, dogs, and hourses. Though FDA-approved for humans, veterinarians often prescribe it for animals to help regulate blood glucose levels. Lantus requires a prescription from your veterinarian. Includes one prefilled 3 mL pen.

Benefits:

• Long-acting insulin helps maintain stable blood sugar levels in diabetic pets for up to 24 hours.
• Delivers a precise, dialed dose every time for consistent blood sugar control.
• Made for use with small, thin needles for more comfortable injections.
• Large print dosing window makes it easier to read and confirm dosage.
• Push button injection offers a simpler alternative to vials and syringes.

How does Lantus SoloStar (insulin glargine injection) U-100 Pen work?

The Lantus SoloStar pen works to mimic the body’s natural insulin by releasing slowly over 24 hours, helping to maintain stable glucose levels throughout the day and night. Taken once daily, Lantus supports A1C reduction when used alongside diet and exercise.

Caution:

Lantus should only be used under the guidance of a licensed veterinarian. Do not use during episodes of hypoglycemia or in pets with known hypersensitivity to insulin glargine or its excipients. Monitor blood glucose levels closely when initiating or adjusting dosage. Never share syringes, needles, or pens between animals.

How should I store this product?

BEFORE FIRST USE: Refrigerate new pens at 36°F to 46°F. Do NOT freeze, do not use Lantus if it has been frozen. AFTER FIRST USE: Do NOT put your pen back in the refrigerator, store at room temperature below 86°F. Keep your pen away from heat or light. Store your pen with the pen cap on. Do NOT store your pen with the needle attached. Discard 28 days after its first use, even if it still has insulin inside it.GENERAL CARE: Avoid dropping your pen against hard surfaces. Do not attempt to repair a damaged pen — replace it. Protect your pen from dust and dirt, wipe the outside with a damp cloth (water only). Do NOT soak, wash, or lubricate your pen.

What is the most important information I should know about Lantus SoloStar (insulin glargine injection) U-100 Pen?

Do not use Lantus if your pet is experiencing low blood sugar or is allergic to insulin glargine. Contact your veterinarian immediately if you notice signs of hypoglycemia such as weakness, stumbling, seizures, or unresponsiveness, or signs of an allergic reaction like facial swelling or difficulty breathing.

What should I discuss with my veterinarian before giving Lantus SoloStar (insulin glargine injection) U-100 Pen to my pet?

Tell your veterinarian if your pet is allergic to insulin or any of the ingredients in Lantus. Be sure to tell your veterinarian if your pet takes TZDs (thiazolidinediones). Inform them if your pet has liver or kidney disease, heart failure, other heart problems, or a history of low blood sugar episodes. Notify your veterinarian if your pet is pregnant, nursing, or if you plan to breed your pet. Also mention any other medications your pet is taking, including prescription drugs, over-the-counter medicines, vitamins, or herbal supplements, as these can affect blood sugar levels.

How should Lantus SoloStar (insulin glargine injection) U-100 Pen be given/administered?

Inject Lantus SoloStar subcutaneously (under the skin) once daily at the same time. Do not inject into muscle or vein, and never mix or dilute with other insulin or solutions. Rotate injection sites—abdomen, thighs, or outer upper arms—and avoid areas that are bruised, scarred, or damaged.Wash your hands before use and confirm the insulin is clear and colorless; do not use if cloudy or contains particles. Always attach a new needle before each use, never share pens or needles, and follow your veterinarian’s dosing instructions.

What are the potential side effects of Lantus SoloStar (insulin glargine injection) U-100 Pen?

If any of the following serious side effects occur, stop giving Lantus and seek emergency veterinary medical attention: an allergic reaction (rash over the whole body, trouble breathing, swelling of the face, tongue, or throat), shortness of breath, extreme drowsiness, dizziness, or confusion.Call your veterinarian at once if your pet has any new or worsening symptoms such as shaking, sweating, fast heartbeat, or blurred vision, which may indicate dangerously low blood sugar (hypoglycemia). Hypoglycemia is the most common side effect of insulin and can be serious or life-threatening.Other possible side effects may include swelling, weight gain, low potassium levels, injection site reactions (including changes in fat tissue at the injection site), and allergic reactions. Other side effects may also occur. Talk to your veterinarian about any reaction that seems unusual or bothersome to the animal.

What happens if I miss giving a dose of Lantus SoloStar (insulin glargine injection) U-100 Pen?

A single missed dose can cause temporary signs, but it is usually not life-threatening. Contact your veterinarian as soon as possible for advice on when to give your animal’s next dose. Never double-up on doses, as this will cause an overdose. If you cannot reach your veterinarian and your animal is eating and acting normally, give your animal the usual dose at the next regularly scheduled time.

What happens if I overdose my pet on Lantus SoloStar (insulin glargine injection) U-100 Pen?

An overdose can cause severe hypoglycemia (low blood sugar), which is an emergency. Signs include weakness, trembling, confusion, seizures, or coma. Contact your veterinarian or an emergency clinic immediately. If you cannot reach them, call the ASPCA Animal Poison Control Center at (888) 426-4435 (fees may apply). If your pet is conscious, offer food or rub a sugary substance (like honey) on the gums while seeking veterinary care. Do not attempt to feed an unconscious pet.

What special precautions are there?

Do not mix Lantus with other insulins or solutions. Rotate injection sites and never inject into muscle or vein. Use only as directed by your veterinarian. Insulin may be used in pregnant or lactating pets under veterinary supervision.

What should I avoid while giving Lantus SoloStar (insulin glargine injection) U-100 Pen to my pet?

Do not skip doses or change the dose without veterinary guidance. Avoid injecting into bruised, scarred, or damaged skin. Do not reuse needles or share pens between pets. Never use insulin that is expired, cloudy, or contains particles. Avoid exposing the pen to extreme heat or freezing temperatures.

What other drugs will affect Lantus SoloStar (insulin glargine injection) U-100 Pen?

Lantus SoloStar may interact with corticosteroids (prednisone, dexamethasone), progestogens (megestrol), and certain diuretics (furosemide), which can increase blood sugar and reduce insulin effectiveness. Drugs that lower blood sugar, such as other insulins or oral hypoglycemics (glipizide, metformin), can increase the risk of hypoglycemia. Thiazolidinediones (pioglitazone, rosiglitazone), otherwise known as AZDs, should be avoided or used with caution, as they may cause fluid retention and worsen heart failure. Beta-blockers (metoprolol), ACE inhibitors (lisinopril), and salicylates (aspirin) may also alter insulin requirements. Do not give any other prescription or over-the-counter medications, including supplements or herbal products, without first consulting your veterinarian.